The biomechanical parameters of distraction can be divided into three categories: 1) extrinsic or fixator-related factors, 2) intrinsic or tissue-related factors, and 3) device orientation (Samchukov et al., 1998c, Cope et al., 1998). Numerous extrinsic parameters affect the mechanical properties of the distraction appliance and stability of bone segment fixation. These parameters include the number, length, and diameter of fixation pins, the rigidity of the distraction device, material properties of the device, etc. Intrinsic parameters are also important factors that affect the quality of the forming distraction regenerate. They include the geometric shape, cross-sectional area, and density of the distracted bone segments; the length of the distraction regenerate; as well as the tension developing within the soft tissue envelope, which includes muscles, ligaments, and fascia. Another critically important biomechanical parameter affecting the successful application of distraction osteogenesis is the orientation of the distraction device, and consequently the distraction vector, relative to the anatomical axis of the bone segments to be distracted.